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The end goal is simply to test whether or not the stack stays intact after failure of one of the stack interfaces (PIC slot 0 ports 46 and 47, in this case).
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Background Chromium picolinate (Cr(pic)3) is advocated as adjuvant therapy for impaired glycemic control, despite concerns for DNA damage.
MX960 Flexible PIC Concentrator Description | Juniper Networks
A Flexible PIC Concentrator (FPC) occupies two Dense Port Concentrator (DPC) slots on an MX Series router. The MX960 router has 11 dedicated DPC slots and one multifunction slot that supports either a DPC, FPC, or Switch Control Board (SCB). The dedicated DPC slots are numbered 0 though 5, and 7 though 11, left to right. The multifunction slot is labeled 2/6. Up to six FPCs can be installed vertically in any two slots that support FPCs (see Figure 1). The interface corresponds to the lowest numbered DPC slot for which the FPC is installed.
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After the Virtual Chassis port is created, it is renamed vcp-slot/pic/port, and the line card associated with that port comes online.
Room-temperature waveguide-integrated photodetector using bolometric effect for mid-infrared spectroscopy applications | Light: Science & Applications
Waveguide-integrated mid-infrared (MIR) photodetectors are pivotal components for the development of molecular spectroscopy applications, leveraging mature photonic integrated circuit (PIC) technologies. Despite various strategies, critical challenges still remain in achieving broadband photoresponse, cooling-free operation, and large-scale complementary-metal-oxide-semiconductor (CMOS)-compatible manufacturability. To leap beyond these limitations, the bolometric effect – a thermal detection mechanism – is introduced into the waveguide platform. More importantly, we pursue a free-carrier absorption (FCA) process in germanium (Ge) to create an efficient light-absorbing medium, providing a pragmatic solution for full coverage of the MIR spectrum without incorporating exotic materials into CMOS. Here, we present an uncooled waveguide-integrated photodetector based on a Ge-on-insulator (Ge-OI) PIC architecture, which exploits the bolometric effect combined with FCA. Notably, our device exhibits a broadband responsivity of 28.35%/mW across 4030–4360 nm (and potentially beyond), challenging the state of the art, while achieving a noise-equivalent power of 4.03 × 10−7 W/Hz0.5 at 4180 nm. We further demonstrate label-free sensing of gaseous carbon dioxide (CO2) using our integrated photodetector and sensing waveguide on a single chip. This approach to room-temperature waveguide-integrated MIR photodetection, harnessing bolometry with FCA in Ge, not only facilitates the realization of fully integrated lab-on-a-chip systems with wavelength flexibility but also provides a blueprint for MIR PICs with CMOS-foundry-compatibility. This work demonstrates a room-temperature waveguide-integrated mid-infrared (>4 µm) photodetector on a Ge-on-insulator platform using the bolometric effect. It achieves ultrabroadband responsivity and label-free gas sensing on a monolithic chip with a CMOS-compatible solution.
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Do not leave a PIC slot empty in order to avoid critical thermal alarms relating to overheating of individual components.
Effects of chromium picolinate on glycemic control and kidney of the obese Zucker rat | Nutrition & Metabolism
Background Chromium picolinate (Cr(pic)3) is advocated as adjuvant therapy for impaired glycemic control, despite concerns for DNA damage. Potential toxicity of Cr(pic)3 should be greater for the kidney that accumulates chromium. Therefore, we tested the hypothesis that Cr(pic)3 treatment of obese Zucker rats (OZR) exacerbates renal abnormalities associated with dysglycemia. Methods Male OZR were treated with diets lacking or containing 5 and 10 mg/kg of chromium, as Cr(pic)3, for 20 weeks; lean Zucker rats (LZR) served as controls. Glycemic and renal effects of Cr(pic)3 were determined in the context of indices of oxidative stress and inflammation. Results The OZR displayed increased fasting plasma glucose and insulin in association with enlarged pancreatic islets exhibiting collagen and periodic acid Schiff-positive deposits compared to LZR; Cr(pic)3 treatment did not affect these parameters. The OZR, irrespective of Cr(pic)3, excreted more albumin than LZR. Also, other indices of renal function or histopathology were not affected by Cr(pic)3 treatment. Urinary excretion of 8-hydroxydeoxyguanosine (8-OHdG), an index of oxidative DNA damage, was greater in the OZR than LZR; dietary Cr(pic)3 treatment attenuated 8-OHdG excretion. However, immunostaining of kidney for 8-OHdG revealed similar staining pattern and intensity, despite significant renal accumulation of chromium in Cr(pic)3-treated groups. Finally, increased renal nitrotyrosine and cyclooxygenase-2 levels and urinary excretion of monocyte chemoattractant protein-1 of OZR were partially reversed by Cr(pic)3 treatment. Conclusion Dietary Cr(pic)3 treatment of OZR does not beneficially influence glycemic status or increase the risk for oxidative DNA damage; rather, the treatment attenuates indices of oxidative stress and inflammation.
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